Two Unusual Presentations of Childhood Brucella Cases

Two Unusual Presentations of Childhood Brucella Cases

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Introduction: Brucellozis is still a common infectious disease in our country and sometimes it may be presented with uncommon clinical manifestations.Case 1: A ten years old male was presented to our clinic with complaints of malaise, weight loss, petechia, and bleeding of gums.On physical examination cervical lymphadenopathy and hepatosplenomegaly had been detected and in complete blood count pancytopenia was found.

admitted to our clinic.In bone marrow aspiration hypocellular bone marrow was seen.His Brucella agglutination test was positive at 1:1280 titer and the blood culture was positive for Brucella mellitensis.

The pancytopenia was resolved after the antibiotherapy.Case 2: A nine-year-old female was Lotions referred to our clinic with tachycardia, who had the cardiac rate of 136/min.The electrocardiography showed sinusal tachycardia and echocardiography was normal, no endocarditis or pericarditis Accessories was present.

She had complaints of fatigue and lassitude for the last month.Her brucella agglutination test was positive at 1:1280 titer and blood culture was negative.After antibiotherapy her symptoms regressed, cardiac rate decreased to 80-100/min.

Isolated tachycardia may be the early manifestaion of brucellosis in children which has not been reported previously.Conclusion: Brucellosis is a rare cause of pancytopenia, it should be considered in differential diagnosis with pancytopenia of children.Brucellosis was known to be involved cardiovascular system, but tachycardia which was not due to fever as the only sign of disease has not been reported previously made our case very interesting.

(Journal of Current Pediatrics 2010; 8: 39-43).